“Hepatitis in young children is not uncommon and it is not uncommon for the cause of some cases of hepatitis in children to remain unknown,” the health ministry said.
He added that no unusual increase or trend has been observed in the number of children with hepatitis of unknown cause.
Although the cause of hepatitis in the three cases in Singapore has not been identified, that does not mean they are linked to the global outbreak, the health ministry said.
“We continue to monitor the situation closely and have advised all doctors to be vigilant for young children with signs and symptoms of hepatitis whose cause cannot be identified.”
The first cases of acute hepatitis of unknown cause in children were identified at an Alabama hospital in October 2021, when five patients were admitted with liver damage.
Since then, cases have been reported in several countries, including Japan, Indonesia, the United Kingdom, Spain and France.
Many affected children are aged 10 and under, and the youngest was one month old.
Common symptoms include abdominal pain, diarrhea and vomiting, followed by jaundice, which is characterized by yellowing of the skin or the whites of the eyes.
Affected children may also experience fatigue, loss of appetite, dark urine, pale stools, and joint pain.